A huge amount of data is produced daily from drug sensitivity screens or protein/ligands 3D structural interaction screens. However, from this data produced, only a very small subset of datasets are published and made publicly available. The majority of data produced is lost due to lack of annotation/standardisation that would make the data FAIR and re-usable for all. Furthermore, structural data and bioactivity data are so far not interconnected and can not be easily integrated.
In this Demonstrator project, scientists from different research infrastructures (Instruct-ERIC, EU-OPENSCREEN, EATRIS, ELIXIR, EU-EBI ) collaborated to develop a set of tools to increase the FAIRness of chemical biology data and structural data and to enable the integration of structural biology data and chemical biology data to increase access and re-use of resources.
CIRMMP
CSC
DIAMOND (Rachael Skyner)
EATRIS (Jing Tang)
EMBL EBI (Andrew Leach)
EMBL Grenoble
Fraunhofer IME (P. Gribbon/A. Zaliani)
IMG (Ctibor Skuta)
IMIM
When we came to EOSC-Life, what we had really was a prototype of an application with some ideas of how we might help our users to access and use fragment screening data but we didn’t really have a well-defined set of goals…in fact we might not have even known what we wanted to achieve. And what EOSC-Life’s really allowed us to do is to find what those goals are and achieve them.
— Rachael Skyner
Attending the workshop and hackathon was a great way to precipitate and catalyse discussions with the EOSC community and that led to the development of whole new approaches within Fragalysis which was extremely good… I think the general experience with EOSC-life, I’m biased as I’m leader of work package one, but it’s a unique opportunity to work across different scientific domains and different resource providers.
— Phil Gribbon